Pesquisa | BVS Violência e Saúde

1.

Identification of human exT_reg cells as CD16⁺CD56⁺ cytotoxic CD4⁺ T cells.

Freuchet, Antoine; Roy, Payel; Armstrong, Sujit Silas; Oliaeimotlagh, Mohammad; Kumar, Sunil; Orecchioni, Marco; Ali, Amal J; Khan, Amir; Makings, Jeffrey; Lyu, Qingkang; Winkels, Holger; Wang, Erpei; Durant, Christopher; Ghosheh, Yanal; Gulati, Rishab; Nettersheim, Felix; Ley, Klaus.

Nat Immunol ; 24(10): 1748-1761, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37563308

2.

A CD22-Shp1 phosphatase axis controls integrin ß₇ display and B cell function in mucosal immunity.

Ballet, Romain; Brennan, Martin; Brandl, Carolin; Feng, Ningguo; Berri, Jeremy; Cheng, Julian; Ocón, Borja; Alborzian Deh Sheikh, Amin; Marki, Alex; Bi, Yuhan; Abram, Clare L; Lowell, Clifford A; Tsubata, Takeshi; Greenberg, Harry B; Macauley, Matthew S; Ley, Klaus; Nitschke, Lars; Butcher, Eugene C.

Nat Immunol ; 22(3): 381-390, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33589816

3.

Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.

Kiss, Máté G; Papac-Milicevic, Nikolina; Porsch, Florentina; Tsiantoulas, Dimitrios; Hendrikx, Tim; Takaoka, Minoru; Dinh, Huy Q; Narzt, Marie-Sophie; Göderle, Laura; Ozsvár-Kozma, Mária; Schuster, Michael; Fortelny, Nikolaus; Hladik, Anastasiya; Knapp, Sylvia; Gruber, Florian; Pickering, Matthew C; Bock, Christoph; Swirski, Filip K; Ley, Klaus; Zernecke, Alma; Cochain, Clément; Kemper, Claudia; Mallat, Ziad; Binder, Christoph J.

Immunity ; 56(8): 1809-1824.e10, 2023 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-37499656

4.

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.

Spann, Nathanael J; Garmire, Lana X; McDonald, Jeffrey G; Myers, David S; Milne, Stephen B; Shibata, Norihito; Reichart, Donna; Fox, Jesse N; Shaked, Iftach; Heudobler, Daniel; Raetz, Christian R H; Wang, Elaine W; Kelly, Samuel L; Sullards, M Cameron; Murphy, Robert C; Merrill, Alfred H; Brown, H Alex; Dennis, Edward A; Li, Andrew C; Ley, Klaus; Tsimikas, Sotirios; Fahy, Eoin; Subramaniam, Shankar; Quehenberger, Oswald; Russell, David W; Glass, Christopher K.

Cell ; 151(1): 138-52, 2012 Sep 28.

Artigo em Inglês | MEDLINE | ID: mdl-23021221

5.

Developing Neutrophils Must EatThemselves!

Fan, Zhichao; Ley, Klaus.

Immunity ; 47(3): 393-395, 2017 09 19.

Artigo em Inglês | MEDLINE | ID: mdl-28930652

6.

The expanding family of neutrophil-derived extracellular vesicles.

Marki, Alex; Ley, Klaus.

Immunol Rev ; 312(1): 52-60, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35665941

7.

De-stressing plaques attenuates atherosclerosis progression.

Nettersheim, Felix Sebastian; Ley, Klaus.

Trends Immunol ; 43(8): 601-603, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35840527

8.

Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling.

Frias-Anaya, Eduardo; Gallego-Gutierrez, Helios; Gongol, Brendan; Weinsheimer, Shantel; Lai, Catherine Chinhchu; Orecchioni, Marco; Sriram, Aditya; Bui, Cassandra M; Nelsen, Bliss; Hale, Preston; Pham, Angela; Shenkar, Robert; DeBiasse, Dorothy; Lightle, Rhonda; Girard, Romuald; Li, Ying; Srinath, Abhinav; Daneman, Richard; Nudleman, Eric; Sun, Hao; Guma, Monica; Dubrac, Alexandre; Mesarwi, Omar; Ley, Klaus; Kim, Helen; Awad, Issam A; Ginsberg, Mark H; Lopez-Ramirez, Miguel Alejandro.

Arterioscler Thromb Vasc Biol ; 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38660801

9.

Molecular mechanisms of leukocyte ß2 integrin activation.

Wen, Lai; Moser, Markus; Ley, Klaus.

Blood ; 139(24): 3480-3492, 2022 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-35167661

10.

HGF Guides T Cells into the Heart.

Wolf, Dennis; Li, Jie; Ley, Klaus.

Immunity ; 42(6): 979-81, 2015 Jun 16.

Artigo em Inglês | MEDLINE | ID: mdl-26084015

11.

Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease.

Lai, Catherine Chinhchu; Nelsen, Bliss; Frias-Anaya, Eduardo; Gallego-Gutierrez, Helios; Orecchioni, Marco; Herrera, Victoria; Ortiz, Elan; Sun, Hao; Mesarwi, Omar A; Ley, Klaus; Gongol, Brendan; Lopez-Ramirez, Miguel Alejandro.

Circ Res ; 131(11): 909-925, 2022 11 11.

Artigo em Inglês | MEDLINE | ID: mdl-36285625

12.

Immunodominant MHC-II (Major Histocompatibility Complex II) Restricted Epitopes in Human Apolipoprotein B.

Roy, Payel; Sidney, John; Lindestam Arlehamn, Cecilia S; Phillips, Elizabeth; Mallal, Simon; Armstrong Suthahar, Sujit Silas; Billitti, Monica; Rubiro, Paul; Marrama, Daniel; Drago, Fabrizio; Vallejo, Jenifer; Suryawanshi, Vasantika; Orecchioni, Marco; Makings, Jeffrey; Kim, Paul J; McNamara, Coleen A; Peters, Bjoern; Sette, Alessandro; Ley, Klaus.

Circ Res ; 131(3): 258-276, 2022 07 22.

Artigo em Inglês | MEDLINE | ID: mdl-35766025

13.

Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice.

Fan, Zhichao; Pitmon, Elise; Wen, Lai; Miller, Jacqueline; Ehinger, Erik; Herro, Rana; Liu, Wei; Chen, Ju; Mikulski, Zbigniew; Conrad, Douglas J; Marki, Alex; Orecchioni, Marco; Kumari, Puja; Zhu, Yanfang Peipei; Marcovecchio, Paola M; Hedrick, Catherine C; Hodges, Craig A; Rathinam, Vijay A; Wang, Kepeng; Ley, Klaus.

J Immunol ; 208(3): 745-752, 2022 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-35031577

14.

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin; Gonen, Ayelet; Prohaska, Thomas A; Sun, Xiaoli; Diehl, Cody; Määttä, Antti; Gaddis, Dalia E; Bowden, Karen; Pattison, Jennifer; MacDonald, Jeffrey G; Ylä-Herttuala, Seppo; Mellon, Pamela L; Hedrick, Catherine C; Ley, Klaus; Miller, Yury I; Glass, Christopher K; Peterson, Kirk L; Binder, Christoph J; Tsimikas, Sotirios; Witztum, Joseph L.

Nature ; 558(7709): 301-306, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29875409

15.

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin; Gonen, Ayelet; Prohaska, Thomas A; Sun, Xiaoli; Diehl, Cody; Määttä, Antti; Gaddis, Dalia E; Bowden, Karen; Pattison, Jennifer; MacDonald, Jeffrey G; Ylä-Herttuala, Seppo; Mellon, Pamela L; Hedrick, Catherine C; Ley, Klaus; Miller, Yury I; Glass, Christopher K; Peterson, Kirk L; Binder, Christoph J; Tsimikas, Sotirios; Witztum, Joseph L.

Nature ; 561(7724): E43, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-30013121

16.

Single Cell High Dimensional Analysis of Human Peripheral Blood Mononuclear Cells Reveals Unique Intermediate Monocyte Subsets Associated with Sex Differences in Coronary Artery Disease.

Chatterjee, Nandini; Komaravolu, Ravi K; Durant, Christopher P; Wu, Runpei; McSkimming, Chantel; Drago, Fabrizio; Kumar, Sunil; Valentin-Guillama, Gabriel; Miller, Yury I; McNamara, Coleen A; Ley, Klaus; Taylor, Angela; Alimadadi, Ahmad; Hedrick, Catherine C.

Int J Mol Sci ; 25(5)2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-38474140

17.

Kindlin-3 recruitment to the plasma membrane precedes high-affinity ß2-integrin and neutrophil arrest from rolling.

Wen, Lai; Marki, Alex; Roy, Payel; McArdle, Sara; Sun, Hao; Fan, Zhichao; Gingras, Alexandre R; Ginsberg, Mark H; Ley, Klaus.

Blood ; 137(1): 29-38, 2021 01 07.

Artigo em Inglês | MEDLINE | ID: mdl-32777822

18.

Thymus-Derived CD4⁺CD8⁺ Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch.

Winkels, Holger; Ghosheh, Yanal; Kobiyama, Kouji; Kiosses, William B; Orecchioni, Marco; Ehinger, Erik; Suryawanshi, Vasantika; Herrera-De La Mata, Sara; Marchovecchio, Paola; Riffelmacher, Thomas; Thiault, Nicolas; Kronenberg, Mitchell; Wolf, Dennis; Seumois, Gregory; Vijayanand, Pandurangan; Ley, Klaus.

J Immunol ; 207(11): 2720-2732, 2021 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-34740961

19.

Deleting interleukin-10 from myeloid cells exacerbates atherosclerosis in Apoe^-/- mice.

Orecchioni, Marco; Wolf, Dennis; Suryawanshi, Vasantika; Winkels, Holger; Kobiyama, Kouji; Makings, Jeffrey; Kiosses, William B; Ley, Klaus.

Cell Mol Life Sci ; 80(1): 10, 2022 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-36496494

20.

Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells.

Vallejo, Jenifer; Saigusa, Ryosuke; Gulati, Rishab; Armstrong Suthahar, Sujit Silas; Suryawanshi, Vasantika; Alimadadi, Ahmad; Durant, Christopher P; Ghosheh, Yanal; Roy, Payel; Ehinger, Erik; Pattarabanjird, Tanyaporn; Hanna, David B; Landay, Alan L; Tracy, Russell P; Lazar, Jason M; Mack, Wendy J; Weber, Kathleen M; Adimora, Adaora A; Hodis, Howard N; Tien, Phyllis C; Ofotokun, Igho; Heath, Sonya L; Shemesh, Avishai; McNamara, Coleen A; Lanier, Lewis L; Hedrick, Catherine C; Kaplan, Robert C; Ley, Klaus.

BMC Biol ; 20(1): 193, 2022 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-36045343

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